This trip begins and ends in Las Vegas, although you could just as easily choose Phoenix as your starting and ending point. 

The 2,838 mile drive first takes you to Death Valley, then down the Owens Valley past the Sierra Nevada Mountains and Alabama Hills, to a relic of old US 66, Amboy, California.  Joshua Tree National Park isn't far way. 

Then, the route heads east, through Phoenix, over the Apache Trail, and into the wild west town of Globe.  Tucson is next, with stops in Saguaro National Park and a drive up to the oasis of Mount Lemmon. 

From Willcox you can visit Chiricahua National Monument, the Wonderland of Rocks, then pass over what some say is the country's least traveled federal highway, US 191, the Coronado Trail. 

Hit the Wigwam Motel in Holbrook for a night, then hike around the red rock canyons of Sedona. 

Drive into the Grand Canyon, over the Hoover Dam, and you've completed one incredible desert road trip!